Series

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- Dr. George O'Malley: There needs to be some rules.
- Dr. Meredith Grey: So, what we can walk around in our underwear on alternate Tuesdays? Or you could see bras, but not panties? Or are you talking Amish rules? Because if you think you're gonna get Izzie to cover herself...
- Dr. George O'Malley: The amount of flesh exposed is not the point. You have to do something, it's your house.
- Dr. Meredith Grey: It's my mother's house.
- Dr. George O'Malley: Meredith!
- Dr. Meredith Grey: Do you like Izzie? Is that was this is about? You have a crush on Izzie?
- Dr. George O'Malley: Izzie? No! I don't like Izzie. Izzie? No! She's not the one I'm attracted to.
- Dr. Meredith Grey: Not the one. So there's a one?
- Dr. George O'Malley: Look, there just have to be some rules.

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At the end of the day, when it comes down to it, all we really want is to be close to somebody. So this thing, where we all keep our distance and pretend not to care about each other, is usually a load of bull. So we pick and choose who we want to remain close to, and once we've chosen those people, we tend to stick close by. No matter how much we hurt them, the people that are still with you at the end of the day - those are the ones worth keeping. And sure, sometimes close can be too close. But sometimes, that invasion of personal space, it can be exactly what you need.
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Look at this. Everybody wants a life without pain. And what does it get you? She needs to be on a poster somewhere to remind people, pain is there for a reason.
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- Dr. Christina Yang: I need you to help me find the leg!... Aren't boyfriends supposed to help in situations like this?
- Dr. Preston Burke: When we're on duty, I can't be your boyfriend.
- Dr. Christina Yang: So, when we're on duty, I can have sex with someone else?

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- Dr. Meredith Grey: Don't look at me like that.
- Dr. Derek Shepherd: Like what?
- Dr. Meredith Grey: Like you've seen me naked!

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Dr. Meredith Grey: I am an evil mistress.
Dr. George O'Malley: But still... you look nice.
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[Addison is annoyed that Derek has just caught a trout and has brought it inside] Why did you bring a trout into the trailer?
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- Dr. Alex Karev: Why would you want to help me?
- Dr. Isobel "Izzie" Stevens: [Yelling] because it's what jesus would freaking do!

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- Christina: Wait, we'll call each other at least twice a month and we'll text each other all the time.
- Meredith: I hate texting.
- Christina: Don't let Owen get all dark and twisty. Take care of him. And Alex, take care of Alex. He needs to be mocked at least once a day or he'll be insufferable. Don't get on any tiny little planes that can crash or stick your hand in a body cavity that has a bomb in it or off your life to a gunman. Don't do that. Don't be a hero. You're my person. I need you alive. You make me brave. Okay, now we dance it out.

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Sometimes the future changes quickly and completely, and we're left with only the choice of what to do next. We can choose to be afraid of it, to stand there trembling not moving, assuming the worst that can happen or we step forward into the unknown and assume it will be brilliant.
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