- Dr. Derek Shepherd: Do you happen to know what time of year neurosurgeons are the busiest, Dr. Stevens?
- Dr. Isobel "Izzie" Stevens: There's a time of year?
- Dr. Derek Shepherd: There's no hard or fast rule, but brain injuries tend to pile up around the holidays. Like our friend here. Folks fall off their roofs while they string up lights. Or they go skating for the first time in a decade and break their heads open. And every year people drive through blizzards to get to parties where they kiss germ-infected strangers under poisonous mistletoe. And then they get so drunk that they smash their heads through their windshield on their way home. Like I said, there's no hard or fast rule.
Dr. Isobel 'Izzie' Stevens (Katherine Heigl), Dr. Derek Sheperd (Patrick Dempsey)
from the movie "Grey's Anatomy" by TV Series

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